Surgical Management of Skin Cancers in Immunosuppressed Patients
Kevin Emerick, MD
Co-Director, Non Melanoma Skin Cancer Multidisciplinary Care and Program
Associate Professor of Otolaryngology-Head and Neck Surgery
Massachusetts Eye and Ear Hospital
Do you have a recurring unanswered clinical question? Are you unsure how to manage a complex case? Ask our Boston-based experts!
Kevin Emerick, MD
Head and Neck Surgery, Massachusetts Eye and Ear Hospital
Jonathan Schoenfeld, MD, MPH
Radiation Oncology, Brigham and Women’s Hospital
Ann Silk, MD
Medical Oncology, Dana-Farber Cancer Institute
Patrick Mulvaney, MD, MPH
Mohs Surgery, UMass Memorial Health Care
Sarah Arron, MD, PhD
2021 ITSCC Annual Meeting (Virtual)
Saturday, March 20, 2021
Oscar Colegio Memorial Lecture
Rare Skin Cancers in Organ Transplant Recipients: An Update
Dr. Catherine Harwood, MA, PhD, FRCP
Professor of Dermatology, Royal London Hospital and Blizzard Institute, Queen Mary University of London
“No difference in skin cancer rates by transplanted organ type after the initial skin cancer.” Dr. Lee Wheless, Vanderbilt University
“Immunosuppressive regimens with tacrolimus and mTOR inhibitors are associated with an increased risk of cutaneous squamous-cell carcinoma metastases in organ transplant recipients: the SCOPE/ITSCC metastases study.” Dr. Jan Nico Bouwes Bavinck, Leiden University Medical Center
“Expression of CD155, PD-1 and PD-L1 in Non-Melanoma Skin Cancer: Implications for Treatment of Advanced Disease.” Dr. Melodi Whitley, Duke University
“CD73 is an immunometabolic biomarker of poor prognosis in patients with primary cutaneous squamous cell carcinoma and hematologic malignancy.” Dr. Stephanie Jackson Cullison, New York University
“Identification of clinical, intrinsic, extrinsic skin aging factors and MC1R variants predisposing to non-melanoma skin cancer (NMSC) in immunosuppressed organ transplant recipients – a case-control study.” Dr. Liliane Borik-Heil, Medical University of Vienna
“Clinical Outcomes of Atypical Fibroxanthoma and Undifferentiated Pleomorphic Sarcoma in Immunosuppressed Patients.” Dr. Jake Wang, Yale University
Case Presentations: Dr. Patrick Mulvaney, Brigham and Womens' Hospital; Dr. Amarachi Eseonu, Johns Hopkins
Panelists: Dr. Kristin Bibee, Assistant Professor of Dermatology, Johns Hopkins; Dr. Eric Nolley, Assistant Professor of Medicine, Pulmonary and Critical Care, Johns Hopkins; Dr. David Carr, Associate Professor, Mohs Surgery and Dermatologic Oncology, Ohio State University; Dr. John Carucci, Professor of Dermatology, NYU Langone Medical Center
2020 ITSCC Transplant Symposium at the Annual Meeting of the Society for Investigative Dermatology
September 26, 2020
Oscar Colegio Memorial Lecture
Update on Transplant Medicine in the Era of COVID-19
Richard Formica, MD
Professor of Medicine and Surgery, Director of Transplant Medicine, Yale University School of Medicine, President of the American Society of Transplantation.
"Acitretin for prevention of keratinocyte carcinoma in solid organ transplant dermatology service,” Katherine Allnutt, Skin Health Institute, Carlton, Victoria.
"Development of consensus-based recommendations in the prevention of cutaneous squamous cell carcinoma in solid organ transplant recipients,” Paul Massey, Brigham and Women’s Hospital, Boston, MA.
"Evaluating the utility of post-surgical radiation therapy for invasive cutaneous squamous cell carcinoma with high risk factors in immunosuppressed patients,” Li-Wei Chang, University of Pittsburgh Medical Center, Pittsburgh, PA.
"A histopathologic scoring system for perineural invasion correlates with adverse outcomes in patients with cutaneous squamous cell carcinoma,” Mariam Totonchy, Yale School of Medicine, New Haven, CT.
"Immunosuppression is not an independent risk factor for poor outcomes in cutaneous squamous cell carcinoma when stratified by Brigham and Women’s tumor stage,” Daniel O’Connor, Brigham and Women’s Hospital, Boston, MA.
"Adjuvant Radiation following Mohs Surgery for a High-Stage CSCC,” Patrick Mulvaney, Brigham and Women’s Hospital, Boston, MA.
"Delays in Skin Cancer Care during COVID-19 Pandemic: Melanoma in a Lung Transplant Recipient,” Kenneth Yu, Brigham and Women’s Hospital, Boston, MA.
"Undifferentiated Pleomorphic Sarcoma in a Renal Transplant Recipient,” Sherry Yu, Yale School of Medicine New Haven, CT.
Transplant Dermatology Clinics: Building and Optimizing Your Practice
Reaching Consensus on Management of Field Cancerization
Thursday, February 15, 2018
San Diego, California, USA
ITSCC Transplant Dermatology Symposium at SID 2017
ITSCC colleagues joined together for the second annual ITSCC Transplant Dermatology Symposium on Thursday, April 27 at the annual meeting of the Society for Investigative Dermatology in Portland, Oregon. The symposium was directed by Oscar Colegio, MD, PhD. Four oral abstracts were presented at this Symposium:
Genomic analysis reveals drivers of high-risk subsets of cutaneous squamous cell carcinoma
Tran Nguyen, H. Lee Moffitt Cancer Center & Research Institute, Kimal Rajapakshe, Baylor College of Medicine, Vida Chitsazzadeh, University of Texas Health Sciences Center Houston, Kimberly Truong, H. Lee Moffitt Cancer Center & Research Institute, Chrysalyne Schmults, Harvard Medical School, AP South, TJU, Raymond Cho, University of California, San Francisco, Cristian Coarfa, Baylor College of Medicine, K Tsai, RDEB SCC Sequencing Consortium.
Risk factors of high frequency basal cell carcinoma: Gender, histologic subtypes, anatomic distribution, and associated immunosuppression
Karen Kuo, Stanford University School of Medicine, Hyunje Cho, Stanford University School of Medicine, Prag Batra, Stanford University School of Medicine, Shufeng Li, Stanford University School of Medicine, Kerri Rieger, Stanford Dermatology, Jean Tang, Stanford University, Kavita Sarin, Stanford University.
Cutaneous infection rates are not affected by chronic HIV(+) or HCV(+) coinfection in organ transplant recipients
Kumar Nadhan, Drexel Dermatology, Scott Shipman, Drexel Dermatology, Erin Buchanan, Drexel Dermatology, Gregory Malat, Drexel Surgery, Alden Doyle, University of Virginia, Christina Chung, Drexel Dermatology
IL-22 promotes early aggressive behavior of cutaneous squamous cell carcinoma (SCC); A murine xenograft model
Melody Abikhair, Dept of Derm, NYU Langone Med Ctr, Nazanin Roudiani, Dept of Derm, NYU Langone Med Ctr, Alexis Santana, Dept of Derm, NYU Langone Med Ctr, Jie Chen, Inst for Ped Urol, Weill Cornell Medicine, Diane Felsen, Inst for Ped Urol, Weill Cornell Medicine, John Carucci, Dept of Derm, NYU Langone Med Ctr.
Congrats to all on a successful event.
ITSCC Members Present “Topics in Transplant” at 2017 ACMS Annual Meeting
ITSCC Past President Fiona Zwald, MD, MRCPI moderated a session, “Topics in Transplant from ITSCC” at the 2017 Annual Meeting of the American College of Mohs Surgery at the Hilton San Francisco Union Square on Saturday, April 29.
Zwald and speakers Matthew Fox, MD and Justin Leitenberger, MD discussed the importance of obtaining a medical and drug history in the evaluation of an immunosuppressed patient who presents with an aggressive skin cancer; description of pre-op and post-op management of aggressive skin cancer in immunosuppressed patients; and use of adjuvant therapies in the immunosuppressed patient with skin cancer.